
Causes of CKD
Ngā take mō te māuiuitanga whatumanawa karioi
Some people are more at risk of getting CKD. People who are in the higher risk group include those who:
If you or a member of your whānau (family) are in one of these groups, talk to your general practice team about being tested for kidney problems. Also find out what you can do to keep them healthy and functioning well.
The 2 commonest causes of kidney disease are diabetes and high blood pressure.
Diabetes
When your blood sugar is raised, it causes damage to many blood vessels in your body, including the blood vessels in your kidneys.
About 1 in 3 people with diabetes will end up with some kidney damage.
Kidney disease caused by diabetes is called diabetic nephropathy.
Read more about diabetes & kidney disease.
High blood pressure
High blood pressure damages the small vessels that take blood to the kidney filters and can also damage the filters themselves.
Other causes
- Kidney inflammation called glomerulonephritis is a group of diseases that affects the filtering units in your kidneys.
- Polycystic kidney disease causes cysts to form in your kidneys. This is an inherited disease, which means it is passed down from your parents.
- Lupus and other diseases that affect your body's immune system can also affect your kidneys.
- Obstructions or blockages in the flow of urine caused by kidney stones or an enlarged prostate gland can affect your kidneys.
- Urinary reflux where the urine flows back from your bladder to your kidneys can cause scarring in your kidneys.
- Repeated kidney infections can lead to long-term kidney problems.
- Long term regular use of pain-relieving medicines called anti-inflammatories (NSAIDS) can harm your kidneys.
HealthInfo recommends the following pages
On the next page: Treating CKD
Written by HealthInfo clinical advisers. Last reviewed March 2025.
Sources
The information in this section comes from the following sources, some of which may be clinically complex or not available to the general public
Healthify He Puna Wairoa – Chronic kidney disease (CKD). Retrieved February 2021.
Healthify He Puna Wairoa – Acute kidney injury. Retrieved November 2024.
NHS – Acute kidney injury. Retrieved November 2024.
NHS – Chronic kidney disease. Retrieved February 2021.
Image and embedded video sources
Blood pressure measurement image from Shutterstock (image ID 93341521). February 2016.
Illustration showing the kidneys in position in the body from Shutterstock (image ID 1363551152). July 2021.
Image of a man having dialysis from Shutterstock (image ID 166957085). July 2021.
Polycystic kidney disease illustration from Shutterstock (image ID 248220016). January 2016.
Understanding kidney disease video from Kidney Health NZ on YouTube.
Urinary system illustration from Shutterstock (image ID 179481320). April 2019.
Your kidneys illustration provided by Medical Illustrations, Te Whatu Ora Waitaha. September 2015.
Page reference: 203155
Review key: HIKID-202879