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HealthInfo Waitaha Canterbury

Midazolam nasal spray

Being short of breath or breathless can be common and upsetting for people receiving palliative care. It can cause panic and anxiety. Midazolam can help to reduce that feeling of panic and anxiety. Your doctor or nurse can also sometimes advise you to use it for other reasons.

You spray midazolam into your nostrils and the medication is quickly absorbed into the lining of your nose. The medication achieves its full effect within 10 minutes.

How to use the spray

Possible side effects

Midazolam can make you feel drowsy.


Do not drive a car or operate heavy machinery if you're sleepy.

Sometimes people do not like the taste at the back of their throat or the sensation in their nose, but this doesn't last long.

Midazolam can also cause nasal and eye irritation.

Keep a record of use

Keep a record of when you use your midazolam spray so your doctor can check if it's working well for you. You should record:

If you have any concerns about using the midazolam spray, see your GP.

Based on Using midazolam nasal spray, a patient/carer guide, Hutt Valley DHB. Adapted by HealthInfo clinical advisers. Last reviewed November 2020.

Page reference: 300573

Review key: HIPAL-17434