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HealthInfo Canterbury

MGUS

PÅ«mua rereke ki te toto (MGUS)

Blood test with formMGUS stands for monoclonal gammopathy of unknown significance. It's a benign (non-cancerous) condition where the body makes an abnormal protein, called a paraprotein. This abnormal protein is found in your blood or urine.

We do not know what causes MGUS. The chance of developing it increases with age.

MGUS doesn't cause any symptoms, so it's only picked up from blood or urine tests taken for other reasons.

MGUS doesn't usually need any treatment. In most people, it stays stable and never causes any problems. But if you've been diagnosed with MGUS, it's important to have ongoing check-ups, as occasionally MGUS can develop into a cancer such as myeloma or lymphoma. Your general practice team will usually follow up with blood and urine tests every six to 12 months.

See your general practice team if you have any of these symptoms:

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Written by HealthInfo clinical advisers. Last reviewed February 2023.

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Page reference: 62267

Review key: HIMGU-16173