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HealthInfo Canterbury


MGUS stands for monoclonal gammopathy of unknown significance. It becomes more common as we get older. It is not cancer.

In this condition your body makes too much of a type of antibody. It happens when the plasma cells in your bone marrow don't quite work properly. It is usually picked up on a blood test called protein electrophoresis or immunoglobulins, which you may have for some other reason.

People with MGUS usually don't have any symptoms. However, if you have this your GP should follow up, as occasionally it can lead to a more serious illness, such as myeloma.

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Written by HealthInfo clinical advisers. Endorsed by clinical director, Haematology Department, Canterbury DHB. Last reviewed June 2015.

Page reference: 62267

Review key: HIMGU-16173