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HealthInfo Canterbury

Entecavir (Baraclude)

What does it do?

Entecavir, also known as Baraclude, reduces the amount of hepatitis B virus (HBV) in your body and has been shown to improve the condition of your liver.

How should you take it?

Entecavir comes in tablet and oral suspension form and is taken by mouth without food. Entecavir should be taken at least two hours after a meal or two hours before the next meal and it should be taken with a glass of water. The recommended dosage of entecavir for adults is 0.5 mg once a day. Individuals should tell a doctor about any medical problems before taking this medicine. Patients with impaired kidney function may require dosage adjustment when taking entecavir.

What if you miss a dose?

Take the missed dose as soon as possible and continue as directed, but if it is almost time to take your next dose, skip the dose you missed. Do not take two doses at once to make up for the missed one. Continue taking the medication for as long as your specialist tells you. Stopping the medication may make your hepatitis worse. It is important not to run out of your medication, so you might like to take extra with you if you go on holiday.

Can you take other medicines?

Some medicines, available without prescription, may interact with entecavir.

Tell your pharmacist or doctor about all medicines or treatments that you are taking, including vitamins, herbal products and recreational drugs.

What side effects might you notice?

Side effects

Recommended action

Lactic acidosis, severe nausea and vomiting.

Tell your doctor immediately.

Headache, unusual tiredness or weakness, dizziness, and nausea.

Tell your doctor.

If you notice any other side effects, discuss them with your doctor or pharmacist.

Other information

Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Entecavir should not be used during pregnancy or lactation.

Prepared by Gastroenterology and Infectious Diseases departments at Christchurch Hospital using PILs templates. Nov 2012.

Page reference: 61992

Review key: HIHEP-49691